Sökning: "Medical and Health Sciences Clinical Medicine Cancer and Oncology"
Visar resultat 11 - 15 av 839 avhandlingar innehållade orden Medical and Health Sciences Clinical Medicine Cancer and Oncology.
11. Health hazards and cancer in relation to occupational exposures among Swedish seafarers
Sammanfattning : This thesis explores health hazards for seafarers in the Swedish merchant fleet, and occupational risks for lung cancer, mesothelioma and hematologic malignancy (HM). A special focus has been exposure to benzene and biomarker levels for work on product or chemical tankers during the mid-1990’ies. LÄS MER
12. Diet and gut microbiota in cardiometabolic health: Studies from the Danish Diet, Cancer and Health – Next Generations Cohort and the sub-cohort MAX
Sammanfattning : Cardiometabolic diseases (CMD) are the leading cause of death globally. Diet is a key preventive factor of CMD and a determinant of gut microbiota. Gut microbiota, diet and their interactions have been associated with CMD. In observational studies, diet is measured by self-reported instruments, that need to be validated before use. LÄS MER
13. Molecular mechanisms of nerve-tumor interactions : the intersection of cancer and neurodevelopment
Sammanfattning : A wide range of cancers throughout the body are characterized by high nerve density and invasion of cancer cells within the nerves, a process called perineural invasion (PNI). Work in the field has shown that blocking nerves in organs with tumors leads to improved disease outcomes suggesting that finding ways to block tumor nerves could lead to new treatment approaches. LÄS MER
14. Development of a Cancer Vaccine Targeting Tumor Blood Vessels
Sammanfattning : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. LÄS MER
15. Staging and tumor biological mechanisms of lymph node metastasis in invasive urinary bladder cancer
Sammanfattning : Aim: To study the possibility of detecting lymph node metastasis in locally advanced urinary bladder cancer (UBC) treated with radical cystectomy (RC) by using preoperative positron emission tomography/computed tomography (PET/CT) and peroperative sentinel node biopsy (SNB) technique. We also investigate the clinical significance of macrophage traits expression by cancer cells, M2-macrophage infiltration (MI) in tumor stroma and the immunohistochemical expression of biomarkers in cancer cells in relation to clinicopathologic data. LÄS MER