Sökning: "McKenna"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet McKenna.

  1. 1. Epithelial stem cells in Hutchinson-Gilford progeria syndrome

    Författare :Tomás McKenna; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hutchinson-Gilford progeria syndrome (HGPS) and restrictive dermopathy (RD) are two rare genetic disorders that affect children. Complications from cardiovascular disease, including atherosclerosis, are the most common cause of death in HGPS, which occurs at around 13 years of age. LÄS MER

  3. 2. Divergence, admixture and continuity in the human past : Demographic inference using ancient and modern genomes

    Författare :James McKenna; Mattias Jakobsson; Per Sjödin; Ida Moltke; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Human evolution; population genetics; ancient genomes; population continuity; divergence; Biology with Specialisation in Human Evolution and Genetics; Biologi med inriktning mot människans evolution och genetik;

    Sammanfattning : Demographic forces shaping the genetic variation we observe today can include population divergences, admixture events and continuity through time. The advancement of high-throughput sequencing technologies, together with developments in molecular and bio-informatics methods, mean the number of ancient genomes available for inference has risen steeply. LÄS MER

  4. 3. Oxidative stress on mammalian cell cultures during recombinant protein expression

    Författare :Tomás McKenna; Carl-Fredrik Mandenius; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : When the cell is under stress arising from oxidation, heat, infection, toxic contamination or any other stressful condition, proteins may unfold and expose residues in their structure that under normal physiological conditions are hidden and shielded from chemical reactions.In this licentiate thesis the effects of general oxidative stress on the production of recombinant protein by mammalian cells are considered. LÄS MER

  5. 4. The Prediction of Traffic Accident Involvement from Driving Behavior

    Författare :Anders af Wåhlberg; Lennart Melin; Frank McKenna; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; Psykologi; Psychology; Psykologi;

    Sammanfattning : The aim of the studies was to predict individual traffic accident involvement by the quantification of driving style in terms of speed changes, using bus drivers as subjects. An accident database was constructed from the archives of the bus company whose drivers were used as subjects. LÄS MER

  7. 5. Promoting traffic safety among young male drivers - the role of mental elaboration

    Författare :Birgitta Falk; Henry Montgomery; Ola Svenson; Frank McKenna; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Young drivers; driving behaviour; social influence; persuasion; risk behaviour; intervention; speeding; test-retest effect; traffic safety; Psychology; Psykologi; psykologi; Psychology;

    Sammanfattning : This thesis explores the potential of mental elaboration as a means of decreasing risky driving among young male drivers. Around 600 young male drivers participated in the three studies. LÄS MER