Sökning: "Mats Söderström"

Visar resultat 21 - 25 av 28 avhandlingar innehållade orden Mats Söderström.

  1. 21. Unraveling Mechanisms of Insulin Resistance in Type 2 Diabetes in Human Adipocytes : Role of extracellular signal regulated kinase 1/2 (ERK1/2) and forkhead box protein 01 (FOX01)

    Författare :Meenu Rohini Rajan; Peter Strålfors; Mats Söderström; Olga Göransson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Type 2 Diabetes is characterized by hyperglycemia primarily caused due to insulin resistance in insulin responsive tissues and insufficient production of insulin by the β-cells. Insulin resistance appears to develop first in the expanding adipose tissue during caloric surplus and affects other tissues like liver and muscle by ectopic fat accumulation. LÄS MER

  3. 22. Transcriptional activity of PPARγ in primary human adipocytes

    Författare :Lilian Sauma; Fredrik Nyström; Mats Söderström; Jan Eriksson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The prevalence of obesity is increasing in most parts of the world and is a strong risk factor for the development of insulin resistance, type 2 diabetes and hypertension. Adipose tissue is mainly composed of adipocytes which store energy in the form of triglycerides and release it as free fatty acids. LÄS MER

  4. 23. Wood Plastic Composites made from Modified Wood : Aspects on Moisture Sorption, Micromorphology and Durability

    Författare :Kristoffer Segerholm; Ove Söderström; Magnus Wålinder; Mats Westin; Pia Larsson Brelid; Per Johan Gustafsson; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wood plastic composites; WPC; acetylation; heat treatment; furfurylation; moisture sorption; micromorphology; decay; UV laser; soil test; Biomaterials; Biomaterial;

    Sammanfattning : Wood plastic composite (WPC) materials have seen a continuous market growth worldwide in the last decade. So-called extruded WPC profiles are today mainly used in outdoor applications, e.g. decking, railing and fencing. LÄS MER

  5. 24. The enzymatic machinery of leukotriene biosynthesis : Studies on ontogenic expression, interactions and function

    Författare :Tobias Strid; Sven Hammarström; Mats Söderström; Ralf Morgenstern; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Leukotrienes (LTs) are biologically active arachidonic acid (AA) derivatives generated by the 5-lipoxygenase (5-LO) pathway. They are produced by myeloid cells. 5-LO converts AA to LTA4 in cooperation with 5-LO activating protein (FLAP). LTA4 is converted to LTB4, by LTA4-hydrolase (LTA4H) or to LTC4 by LTC4-synthase (LTC4S). LÄS MER

  7. 25. Leukotriene C4 synthase : studies on oligomerization and subcellular localization

    Författare :Jesper Svartz; Mats Söderström; Sven Hammarström; Colin Funk; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Leukotrienes (LTs) are polyunsaturated fatty acid derivatives formed by oxygenation of arachidonic acid via the 5-lipoxygenase (5-LO) pathway. Upon activation of inflammatory cells 5-LO is translocated to the nuclear envelope where it converts arachidonic acid to the unstable epoxide LTA4. LÄS MER