Sökning: "Matrix"

Visar resultat 21 - 25 av 2853 avhandlingar innehållade ordet Matrix.

  1. 21. About hyaluronan in the hypertrophic heart : studies on coordinated regulation of extracellular matrix signalling

    Författare :Urban Hellman; Anders Waldenström; Stellan Mörner; Anna Engström-Laurent; Lena Jonasson; Umeå universitet; []
    Nyckelord :hyaluronan; hyaluronan synthases; gene expression; extracellular matrix; cardiac hypertrophy; rat wistar; male ; cardiomyocytes; growth factors; fibroblasts; microvesicles; exosomes; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Background. Myocardial hypertrophy is a risk factor for cardiovascular morbidity and mortality. Independent of underlying disease, the cardiac muscle strives in different ways to compensate for an increased workload. This remodelling of the heart includes changes in the extracellular matrix which will affect systolic and diastolic cardiac function. LÄS MER

  3. 22. Studies on extracellular matrix proteins in vascular disease

    Författare :Åsa Ström; Kärlväggsbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; smooth muscle cells; osteopontin; extracellular matrix; atherosclerosis;

    Sammanfattning : The composition of the vascular extracellular matrix (ECM) is altered during remodeling conditions such as atherosclerosis. The changed ECM regulates events that are important for the progression of disease including smooth muscle cell (SMC) behaviour and collagen fiber formation. LÄS MER

  4. 23. Twisting it up the Quantum Way : On Matrix Models, q-deformations and Supersymmetric Gauge Theories

    Författare :Rebecca Lodin; Maxim Zabzine; Taro Kimura; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Matrix models; Virasoro constraints; Virasoro algebra; W algebra; q-deformations; Supersymmetric gauge theories; Theoretical Physics; Teoretisk fysik;

    Sammanfattning : The mathematical framework which quantum field theory constitutes has been very successful in describing nature. As an extension of such a framework, the idea of supersymmetry was introduced. This greatly simplified the mathematical description of the theories, making them more tractable. LÄS MER

  5. 24. Fluid biomarkers of extracellular matrix remodelling across neurological diseases

    Författare :Karolina Minta; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; extracellular matrix; idiopathic normal pressure hydrocephalus; immunoassay; mass spectrometry; radiation-induced brain injury; traumatic brain injury; vascular dementia;

    Sammanfattning : Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. LÄS MER

  7. 25. Structure and Interactions of the Extracellular Matrix Protein PRELP

    Författare :Eva Bengtsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; extracellular matrix; PRELP; heparin; heparan sulfate; perlecan; collagen; cell-binding; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Metabolism; Biokemi;

    Sammanfattning : This thesis describes the structure and interactions of a novel extracellular matrix protein - PRELP (proline arginine-rich end leucine-rich repeat protein). The amino acid sequence of PRELP showed that it belonged to the leucine-rich repeat (LRR) protein family in connective tissues. LÄS MER