Sökning: "Mating type switch"

Hittade 3 avhandlingar innehållade orden Mating type switch.

1. 1. Mating type switching and transcriptional silencing in Kluyveromyces lactis

   Författare :Emad Barsoum; Åström Stefan; Laura Rusche; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mating type switch; transcriptional silencing; alpha3; transposase; Ume6; Mts1; Ras; cAMP; K. lactis; Developmental biology; Utvecklingsbiologi; utvecklingsbiologi; Developmental Biology;

   Sammanfattning : To explore the similarities and differences of regulatory circuits among budding yeasts, we characterized the role of unscheduled meiotic gene expression 6 (UME6) and a novel mating type switching pathway in Kluyveromyces lactis. We found that Ume6 was required for transcriptional silencing of the cryptic mating-type loci HMLα and HMRa. LÄS MER

3. 2. Regulation and mechanism of mating-type switching in Kluyveromyces lactis

   Författare :Naghmeh Rajaei; Stefan Åström; Kenneth Wolfe; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; yeast; mating-type switching; DSB; gene conversion; transposable elements; RAS cAMP pathway; nutrient limitation; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Transposable elements (TEs) have had immense impact on the structure, function and evolution of eukaryotic genomes. The work in this thesis identified Kat1, a novel domesticated DNA transposase of the hAT family in the yeast Kluyveromyces lactis. Kat1 triggers a genome rearrangement that results in a switch of mating type from MATa to MATα. LÄS MER

4. 3. On the Evolution of Reproductive Systems in Neurospora

   Författare :Rebecka Strandberg; Hanna Johannesson; Paul Dyer; Uppsala universitet; []
   Nyckelord :Neurospora; mating type; pheromone receptor; phylogeny; gene expression; heterothallism; homothallism; pseudohomothallism; alternative splicing; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : The aim of this thesis was to study the evolution of reproductive systems and reproductive traits in the fungal genus Neurospora. More specifically, I have investigated the evolutionary forces shaping the genes involved in sexual reproduction, focusing on mating-type (mat) and pheromone receptor (pre) genes. LÄS MER