Sökning: "Mast cell progenitor"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Mast cell progenitor.

  1. 1. Mast Cell Migration in Inflammatory Diseases

    Författare :Niclas Olsson; Gunnar Nilsson; Jaroslaw Dastych; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; inflammation; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cells (MCs) are forceful multifunctional effector cells of the immune system. MCs are normally distributed throughout connective and mucosal tissues, but in several pathological conditions accumulation of MCs occur. LÄS MER

  3. 2. The Role of Chemokines in Mast Cell Migration

    Författare :Mikael Juremalm; Timothy J. Williams; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; calcium flux; chemokines and chemokine receptors; Patologi; Pathology; Patologi; Pathology; patologi;

    Sammanfattning : Mast cells are very potent multifunctional effector cells of the immune system normally distributed throughout connective tissues. An accumulation of mast cells has been described in several pathological conditions such as allergic- and autoimmune inflammations and in certain tumours. LÄS MER

  4. 3. Glioma as an Ecosystem : Studies of Invasion, Onco-miR Addiction and Mast Cell Infiltration

    Författare :Jelena Põlajeva; Bengt Westermark; Ingemar Ernberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioblastoma; mast cell; miR-21; RAP1; CXCL12; SOX2;

    Sammanfattning : Despite recent advances in oncology and extensive research efforts, gliomas remain essentially incurable. Glioblastoma multiforme (GBM, WHO grade IV) is the most common glioma and may arise de novo or progress from a lower-grade lesion. GBM is characterized by invasive growth, aberrant angiogenesis and necrosis. LÄS MER

  5. 4. Mast Cell Progenitor Trafficking in Allergic Airway Inflammation

    Författare :Joakim Dahlin; Jenny Hallgren; Hans-Reimer Rodewald; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; mast cell progenitors; allergy; asthma; allergic airway inflammation; IgE; lung; CD11c;

    Sammanfattning : Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. LÄS MER

  7. 5. New Aspects of Mast Cell Progenitors in Health and Disease

    Författare :Maya Salomonsson; Jenny Hallgren Martinsson; Silvia Bulfone-Paus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitor; Lung function; Bone marrow; Blood; Activation; Chemotactic receptors;

    Sammanfattning : Mast cells are tissue-resident immune cells that are well known for their involvement in asthma and allergy. They originate in the fetal yolk sac, or in the bone marrow. From the bone marrow, they are released as immature progenitors that are transported via the blood circulation to the peripheral tissue, where they mature. LÄS MER