Sökning: "Massively parallel sequencing"
Visar resultat 21 - 25 av 36 avhandlingar innehållade orden Massively parallel sequencing.
21. PCR inhibition mechanisms in forensic DNA analysis
Sammanfattning : In forensic DNA analysis, the polymerase chain reaction (PCR) enables DNAanalysis of minute biological crime scene traces. PCR is an enzymatic reaction for amplification of specific DNA fragments involving both biochemical andbiophysical processes. The main analytical challenge is posed by the nature of the samples of interest. LÄS MER
22. Parallel target selection by trinucleotide threading
Sammanfattning : DNA is the code for all life. Via intermediary RNA the information encoded by the genome is relayed to proteins executing the various functions in a cell. Together, this repertoire of inherently linked biological macromolecules determines all characteristics and features of a cell. LÄS MER
23. Interrogation of Nucleic Acids by Parallel Threading
Sammanfattning : Advancements in the field of biotechnology are expanding the scientific horizon and a promising era is envisioned with personalized medicine for improved health. The amount of genetic data is growing at an ever-escalating pace due to the availability of novel technologies that allow massively parallel sequencing and whole-genome genotyping, that are supported by the advancements in computer science and information technologies. LÄS MER
24. Spatial mapping of bacteria and transcriptomes
Sammanfattning : Novel insights into biological functions and mechanisms, cell networks and evolutionary relationships are gained through development of sequencing technologies and sequencing based applications. Massively parallel sequencing has enabled analysis of big data at gene and protein expression levels, but has also characterized bacterial communities. LÄS MER
25. Single-cell RNA sequencing for subtype discovery in Plasmodium falciparum and mammalian cells
Sammanfattning : Since the dawn of massively parallel sequencing technologies in mid-2000s their utility in profiling the expression of genes in a genome-wide fashion has matured and progressed from cell populations to individual cells. In particular, single-cell RNA sequencing (scRNA-seq) has impacted numerous domains in life sciences and hold immense promise in biology and medicine. LÄS MER