Sökning: "Martin Ott"

Visar resultat 11 - 15 av 17 avhandlingar innehållade orden Martin Ott.

1. 11. Novel methods to study mitochondrial gene expression and homeostasis

   Författare :Magdalena Rzepka; Martin Ott; Christof Osman; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; gene expression; metabolism; biokemi; Biochemistry;

   Sammanfattning : Mitochondria are semi-autonomous organelles that harbor one of the main cellular processes – energy conversion. Nutrients available in the environment are taken up by cells and transformed into metabolites that can be used for synthesis of ATP, the energy currency of the cell. LÄS MER

3. 12. Organization and regulation of mitochondrial gene expression

   Författare :Roger Salvatori; Martin Ott; Benoit Kornmann; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitochondrial gene expression; post-transcriptional regulation; mitochondrial ribosome; protein-protein proximity; BioID; feedback loop; Biochemistry; biokemi;

   Sammanfattning : Mitochondria possess their own genome, remnant of the ancestral eubacterial endosymbiont DNA. This mitochondrial genome encodes mostly few key subunits of the respiratory chain. In order to synthesize these few proteins, mitochondria contain a complete gene expression machinery. LÄS MER

4. 13. Biogenesis of the bc1 complex in mitochondria

   Författare :Katharina Stephan; Martin Ott; Daniel Daley; Erika Fernandez-Vizarra; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Respiratory chain; bc1 complex assembly; mitochondrial protein biogenesis; molecular biology; yeast; Biochemistry; biokemi;

   Sammanfattning : Mitochondria perform a variety of tasks, but the function they are most prominent for is the energy conversion to form ATP, the universal energy equivalent of the cell. The majority of this ATP is created by the oxidative phosphorylation system, consisting of the respiratory chain and the ATP synthase. LÄS MER

5. 14. Mitochondrial translation and its impact on protein homeostasis and aging

   Författare :Tamara Suhm; Martin Ott; Aleksandra Trifunovic; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondrial ribosome; mitochondrial translation accuracy; mitochondrial communication; interorganellar communication; stress signaling; proteostasis; aging; yeast genetics; mitochondrial protein quality control; mitochondrial membrane protein insertion; Biochemistry; biokemi;

   Sammanfattning : Besides their famous role as powerhouse of the cell, mitochondria are also involved in many signaling processes and metabolism. Therefore, it is unsurprising that mitochondria are no isolated organelles but are in constant crosstalk with other parts of the cell. LÄS MER

7. 15. Significance of mitochondrial ultrastructure for bioenergetics

   Författare :Alexandra Toth; Martin Ott; Vladimir Gogvadze; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioenergetics; mitochondrial ultrastructure; respiratory chain; Saccharomyces cereviciae; ATP synthase; apoptosis; cytochrome c; supercomplexes; Biochemistry; biokemi;

   Sammanfattning : Mitochondria are the site where most of the energy from food is converted into adenosine triphosphate (ATP). This process is taking place at the inner membrane (IM) of mitochondria, and is called oxidative phosphorylation, and results in the establishment of a proton motive force (pmf). LÄS MER