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  1. 1. Fundamental Investigations of Supercritical Fluid Chromatography

    Författare :Martin Enmark; Torgny Fornstedt; Arvind Rajendran; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Supercritical Fluid Chromatography; SFC; Modeling; Adsorption Isotherms; Scale-up; Peak Distortion; Injection; Design of Experiments; Perturbation Peak Method; Elution by Characteristic Points Method; Method transfer; Kemi; Chemistry;

    Sammanfattning : This thesis aims at a deeper understanding of Supercritical FluidChromatography (SFC). Although preparative SFC has started to replace Liquid Chromatography (LC) in the pharmaceutical industry - because of its advantages in speed and its less environmental impact - fundamental understanding is still lacking. LÄS MER