Sökning: "Martin Bollmark"

Hittade 1 avhandling innehållade orden Martin Bollmark.

1. 1. Studies on the synthesis of nucleotide analogues containing P-F and P-Se bonds

   Författare :Martin Bollmark; Janusz Rachon; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

   Sammanfattning : In the present work, new synthetic approaches to the synthesis of nucleoside phosphorofluoridate and phosphorofluoridothioate diesters have been developed. These procedures involve either oxidative transformation of the corresponding H-phosphonate or H-phosphonothioate diesters in the presence of fluoride anion or iodine-promoted desulfurization of phosphorothioate or phosphorodithioate diesters in the presence of fluoride anion. LÄS MER