Sökning: "Martha-Lena Müller"

Hittade 1 avhandling innehållade orden Martha-Lena Müller.

1. 1. Role of syntaxin-11 and munc18-2 in lymphocyte cytotoxic granule exocytosis

   Författare :Martha-Lena Müller; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Mutations in genes required for the exocytosis of cytotoxic granules by NK cells and cytotoxic T lymphocytes are associated with early-onset familial hemophagocytic lymphohistiocytosis (FHL). In this project, we examined how certain missense mutations in genes encoding syntaxin-11 and Munc18-2 abolish exocytosis and cause disease. LÄS MER