Sökning: "Marika nestor"
Visar resultat 11 - 14 av 14 avhandlingar innehållade orden Marika nestor.
11. Precision medicine and targeted therapy : Turning the tables on cancer
Sammanfattning : An extended understanding of the molecular characteristics of cancer has led to a revolution within the field of precision medicine. This thesis explores the utilization of two targets for precision medicine, namely, CD44v6 and murine double-minute 2 and X (MDM2/X). LÄS MER
12. Radioimmunodiagnosis of Head and Neck Squamous Cell Carcinomas : Preclinical Studies
Sammanfattning : Despite improvements in treatment, the prognosis for patients with advanced head and neck squamous cell carcinomas (HNSCC) has only improved to a minor degree. To raise the success rate and minimize morbidity further developments in diagnostics are highly desired. Radioimmunodiagnosis could offer a more specific and sensitive diagnostic method. LÄS MER
13. Towards Personalized Cancer Therapy : New Diagnostic Biomarkers and Radiosensitization Strategies
Sammanfattning : This thesis focuses on the evaluation of biomarkers for radio-immunodiagnostics and radio-immunotherapy and on radiosensitization strategies after HSP90 inhibition, as a step towards more personalized cancer medicine. There is a need to develop new tracers that target cancer-specific biomarkers to improve diagnostic imaging, as well as to combine treatment strategies to potentiate synergistic effects. LÄS MER
14. Targeting Human Epidermal Growth Factor Receptors with Drug Conjugates Based on Affibody Molecules
Sammanfattning : Cancer is a major public health challenge and the second leading cause of death in the world, with millions of new cases being diagnosed each year. Traditional cancer treatments such as surgery, radiation therapy, and chemotherapy are many times effective, but may also cause damage to healthy cells, leading to side effects. LÄS MER