Sökning: "Marietta Flores Diaz"

Hittade 1 avhandling innehållade orden Marietta Flores Diaz.

1. 1. A UDP-glucose deficient mutant cell line as a model to study the cytotoxicity of Clostridium perfringens PLC

   Författare :Marietta Flores Diaz; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : A Chinese Hamster fibroblast mutant cell line, deficient in UDP-glucose (UDP-Glc) and hypersensitive to Clostridium perfringens phospholipase C (PLC) was used in this study to determine some of the molecular consequences of a cellular UDP-Glc deficiency. Furthermore, using this cell as a model, structure/function studies were performed to identify residues critical for the cytotoxic activity of PLC. LÄS MER