Sökning: "Marie Ekholm"

Hittade 1 avhandling innehållade orden Marie Ekholm.

1. 1. OX1 Orexin Receptor Signalling to Phospholipases

   Författare :Marie Ekholm; Jyrki Kukkonen; Graeme Milligan; Uppsala universitet; []
   Nyckelord :orexin; phospholipase; Calcium; cell signalling; G protein coupled receptor; ERK; live-cell imaging; arachidonic acid; diacylglycerol;

   Sammanfattning : The neuropeptides orexin-A and orexin-B were discovered in 1998 and were first described as regulators of feeding behaviour. Later research has shown that they have an important role in the regulation of sleep. Two G protein-coupled receptors, OX1 and OX2 orexin receptors, mediate the cellular responses to orexins. LÄS MER