Sökning: "Marie Allen"

Visar resultat 6 - 10 av 10 avhandlingar innehållade orden Marie Allen.

1. 6. Application of Mitochondrial DNA Analysis in Contemporary and Historical Samples

   Författare :Maria Lembring; Marie Allen; Niels Morling; Uppsala universitet; []
   Nyckelord :Forensic genetics; Mitochondrial DNA; HVI HVII; Population database; Haplotype; Haplogroup; Ancient DNA; Historical DNA samples; skeletal remains; Vasa museum; Medieval samples; Copernicus; Göring; Genetik; Genetics;

   Sammanfattning : The mitochondrion is a tiny organelle that is the power supplier of the cell and vital to the functioning of the body organs. Additionally it contains a small circular genome of about 16 kb, present in many copies which makes the mitochondrial DNA more viable than nuclear DNA. LÄS MER

3. 7. Mitochondrial DNA in Sensitive Forensic Analysis

   Författare :Martina Nilsson; Marie Allen; Ulf Gyllensten; Antti Sajantila; Uppsala universitet; []
   Nyckelord :Genetics; Forensic genetics; Mitochondrial DNA; HVI HVII; Nuclear DNA; Quantification; Real-time PCR; Immobilised SSO probe assay; Pyrosequencing; Discrimination power; Coding region; Mixtures; Genetik;

   Sammanfattning : Genetic profiling is commonly performed on the autosomes using multiple DNA markers. Although routine forensic DNA analysis is robust and based on reliable technologies, samples with degraded or limited amounts of DNA often fail. In these cases, the analysis of mitochondrial DNA (mtDNA) can be very valuable due to the high copy number per cell. LÄS MER

4. 8. Molecular Palaeopathology : Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy

   Författare :Emilia Nuorala; Kerstin Lidén; Ingrid Ekenman; Marie Allen; Stockholms universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; molecular palaeopathology; ancient DNA; disease; bacteria; tuberculosis; leprosy; Archaeology subjects; Arkeologiämnen;

   Sammanfattning : This thesis “Molecular Palaeopathology. Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy” deals with molecular palaeopathology, i.e. in this case the use of molecular methods to analyse ancient bacterial DNA in order to get further knowledge of diseases in ancient times. LÄS MER

5. 9. Mitochondrial Genome Analysis Using Next Generation Sequencing for Forensic Applications

   Författare :Kimberly Sturk-Andreaggi; Marie Allen; Antti Sajantila; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondrial DNA; next generation sequencing; massively parallel sequencing; forensic genetics; nuclear mitochondrial DNA segment NUMT ; length heteroplasmy; haplogroup; quality control; population data; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Sammanfattning : Mitochondrial DNA (mtDNA) analysis plays a specialized role in forensic applications, overcoming certain limitations of autosomal DNA markers. The high copy number and uniparental inheritance pattern of mtDNA are advantageous in cases involving shed hairs and aged skeletal elements, especially decades-old missing persons cases. LÄS MER

7. 10. Vaginal prolapse surgery : an epidemiological perspective : studies of native tissue repair versus implants, surgeons´ practical experiences and five year follow-up in the swedish national quality register for gynecological surgery

   Författare :Emil Nüssler; Mats Löfgren; Marie Bixo; Martin Stjernquist; Umeå universitet; []
   Nyckelord :pelvic organ prolapse; Kaplan-Meier curves; long-term follow-up; quality register; questionnaire; patient reported outcome; cystocele; rectocele; colporrhaphy; non-absorbable mesh; surgical experience; hälso- och sjukvårdsforskning; health services research; Obstetrics and Gynaecology; obstetrik och gynekologi;

   Sammanfattning : Background: Pelvic organ prolapse (POP) is a common condition that impacts on quality of life for many women. The mean age of Swedish women operated for POP is 60 years, and with a life expectancy of approximately 84 years this means that the average patient will live 24 years subsequent to the operation. LÄS MER