Sökning: "Marie Öhman"
Visar resultat 11 - 15 av 25 avhandlingar innehållade orden Marie Öhman.
11. Physical contact in physical education : New perspectives and future directions
Sammanfattning : This thesis takes its point of departure in the research field of intergenerational touch in educational settings. Specifically, it is mainly the student perspective of physical contact between teachers and students in physical education (PE) that is of interest. In addition, a scoping review has also been conducted. LÄS MER
12. Regulation and Function of RNA Editing in the Mammalian Brain
Sammanfattning : Adenosine (A) to inosine (I) RNA editing is a widespread post-transcriptional mechanism in eukaryotes that increases the protein diversity. Adenosine deaminases acting on RNA (ADARs) are the enzymes that catalyze this conversion. LÄS MER
13. A-to-I RNA editing : Function and consequences during brain development
Sammanfattning : The aim of my thesis has been to study how A-to-I RNA editing of miRNAs is regulated during brain development and the biological function of these editing events.Using high throughput RNA sequencing, we performed an unbiased search for edited, mature miRNAs in total mouse brain tissue from three developmental stages. LÄS MER
14. The multi-faceted RNA molecule : Characterization and Function in the regulation of Gene Expression
Sammanfattning : In this thesis I have studied the RNA molecule and its function and characteristics in the regulation of gene expression. I have focused on two events that are important for the regulation of the transcriptome: Translational regulation through micro RNAs; and RNA editing through adenosine deaminations. LÄS MER
15. The ADAR editing enzymes as therapeutic targets
Sammanfattning : Editing by deamination of adenosine to inosine (A-to-I) in double-stranded RNA is a common event in the human transcriptome. Altered levels of the essential ADAR1 activity are associated with disease. Children with mutations in the ADAR1 gene suffer from fatal Aicardi-Goutières syndrome (AGS) characterized by aberrant interferon expression. LÄS MER