Sökning: "Maria Sundbäck"

Hittade 1 avhandling innehållade orden Maria Sundbäck.

1. 1. Vaccine strategies based on mycobacterial heat shock protein 65

   Författare :Maria Sundbäck; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mycobacteria; DNA vaccination; Hsp65; T cells; CD8 T cell epitopes;

   Sammanfattning : Mycobacteria can infect macrophages and dendritic cells (DC), where they reside inside the endosomal compartment. The importance of CD4+ T cells in protective immunity against mycobacteria and other intracellular pathogens is well established, and for a long time these cells were thought to be the major defense in controlling an infection. LÄS MER