Sökning: "Maria Millingen"

Hittade 2 avhandlingar innehållade orden Maria Millingen.

  1. 1. Patch-clamp studies of the GABAA receptor using microfluidic methods

    Författare :Maria Millingen; Chalmers University of Technology; []
    Nyckelord :ion channel; microfluidics; GABAA receptor;

    Sammanfattning : Ion channels are membrane proteins that passively transport ions. When activated, conformational changes within the protein lead to opening of a channel pore, and the flow of ions causes a change in the membrane potential. This is the fundamental process behind the generation and transduction of nerve impulses. LÄS MER

  2. 2. Studies of ligand- and temperature-gated ion channels using microfluidic methods

    Författare :Maria Millingen; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; solution exchange; desensitization; temperature-gated; ion channel; temperature control; ligand-gated; TRPV1; GABAA receptor; microfluidics;

    Sammanfattning : This thesis describes the studies of the GABAA receptor, a ligand-gated ion channel, and the ligand- and temperature-gated ion channel TRPV1. The desensitization behavior of both of these proteins has been studied for different conditions, using a microfluidic device for superfusion. LÄS MER