Sökning: "Maria Kakoulidou"

Hittade 1 avhandling innehållade orden Maria Kakoulidou.

  1. 1. T cells and costimulatory factors in myasthenia gravis

    Författare :Maria Kakoulidou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; T cells; Myasthenia gravis MG ; costimulation; autoimmune disease; genetic polymorphism; twin;

    Sammanfattning : The autoimmune disease myasthenia gravis (MG) is characterized by muscle weakness due to a loss of acetylcholine receptors (AChR) at the neuromuscular end plate. Most MG patients have pathogenic antibodies directed against the receptor. We provide further evidence that T cells are important for establishment and continuation of the disease. LÄS MER