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1. 1. Immunotherapy with the anti-EpCAM monoclonal antibody and cytokines in patients with colorectal cancer : a clinical and experimental study

   Författare :Maria Gustafsson Liljefors; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Colorectal carcinoma; monoclonal antibodies; GM-CSF; pharmacokinetics; prognosis; bone marrow micrometastases; cytokeratin-positive cells; Colorectal carcinoma;

   Sammanfattning : The tumor-associated antigen EpCAM (epithelial cell-adhesion molecule) (C017-1A) is over expressed by various human carcinomas, including colorectal carcinoma (CRC). This antigen can be used as a target structure for specific immunotherapy with vaccines and monoclonal antibodies (MAb). LÄS MER