Sökning: "Maria Erlandsson"

Hittade 3 avhandlingar innehållade orden Maria Erlandsson.

  1. 1. Imaging of Enzymes in the Steroid Biosynthetic Pathway : Synthesis of 18F-Labelled Tracers

    Författare :Maria Erlandsson; Bengt Långström; Franklin Aigbirhio; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis deals with the synthesis and development of 18F-labelled alkyl etomidate and vorozole analogues, and their use as positron emission tomography (PET) tracers for the imaging of the steroid enzymes 11β-hydroxylase and aromatase. Two synthetic 18F-labelling approaches to the etomidate and vorozole analogues were developed, and the analogues were evaluated in some biological assays. LÄS MER

  3. 2. Exploring symptom clusters in patients with lung cancer

    Författare :Katarina Karlsson; Maria Larsson; Cecilia Olsson; Ann Erlandsson; Karin Ahlberg; Joakim Öhlén; Karlstads universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer care; oncology nursing; patients with lung cancer; patient-reported outcome measures; symptom assessment; symptom clusters; symptom management; Nursing Science; Omvårdnad;

    Sammanfattning : This thesis explored symptom clusters in patients with lung cancer before, during and after oncological treatment. A literature review and an interview study was used to explore the symptom cluster experience from the patients’ perspective. LÄS MER

  4. 3. A stargazer's guide to neurodegeneration : Astrocytes' role in the propagation of pathological proteins

    Författare :Tobias Mothes; Anna Erlandsson; Martin Ingelsson; Linn Streubel-Gallasch; Maria Grazia Spillantini; Uppsala universitet; []
    Nyckelord :Alzheimer’s disease; Parkinson’s disease; tauopathies; astrocyte; microglia; neuron; tau; amyloid-β; α-synuclein; accumulation; degradation; inflammation; spreading; seeding.; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are characterized by brain accumulation of pathogenic protein aggregates. In the AD brain, amyloid-β (Aβ) and tau form plaques respective tangles, while in the PD brain α-synuclein (α-syn) form Lewy bodies and Lewy neurites. LÄS MER