Sökning: "Marginal zone macrophages"
Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Marginal zone macrophages.
1. Mechanisms involved in macrophage phagocytosis of apoptotic cells
Sammanfattning : Efficient removal of apoptotic cells is critical for development, tissue remodelling, maintenance of homeostasis, and response to injury. Phagocytosis of apoptotic cells is mediated by many phagocytic receptors, soluble bridging molecules, and pro-phagocytic ligands on the surface of apoptotic cells. LÄS MER
2. Defining the role of CD47 and SIRPα in murine B cell homeostasis
Sammanfattning : B cell development is a highly organized process, which commences in the fetal liver during embryogenesis and in the bone marrow (BM) after birth. Surface IgM+ immature B cells emigrate from the BM via the blood stream to the spleen and finally differentiate into conventional mature follicular B (FoB) cells and marginal zone (MZ) B cells. LÄS MER
3. The Importance of Macrophages, Lipid Membranes and Seeding in Experimental AA Amyloidosis
Sammanfattning : Amyloidosis is a group of protein misfolding diseases caused by tissue deposition of fibrillary protein aggregates termed amyloid. Amyloid A (AA) amyloidosis is a systemic form of amyloidosis that occurs as a complication of chronic inflammatory diseases, such as rheumatoid arthritis, familial Mediterranean fever and chronic infections, such as tuberculosis. LÄS MER
4. Role of macrophage receptor MARCO in host defense
Sammanfattning : Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during infection. LÄS MER
5. Autoimmune Regulator Deficient Mice, an Animal Model of Autoimmune Polyendocrine Syndrome Type I
Sammanfattning : Autoimmune diseases develop when the immune system fails to distinguish self from non-self or when the immune system is hypersensitive to endogenous or exogenous danger signals, or when a tissue erroneously sends a danger signal to the immune system. The education of the immune system to distinguish self from non-self is mainly carried out in the thymus and gives rise to central tolerance, whereas the ability to sense a danger or a healthy tissue constitutes peripheral tolerance. LÄS MER