Sökning: "Margarida M. Silva"

Hittade 1 avhandling innehållade orden Margarida M. Silva.

1. 1. Nonlinear Modeling and Feedback Control of Drug Delivery in Anesthesia

   Författare :Margarida M. Silva; Alexander Medvedev; Teresa Mendonça; Torbjörn Wigren; Robain De Keyser; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; anesthesia; drug delivery; feedback control; nonlinear modeling; pharmacokinetics pharmacodynamics; PID control; system identification; Wiener model; Elektroteknik med inriktning mot reglerteknik; Electrical Engineering with specialization in Automatic Control;

   Sammanfattning : General anesthesia is a drug-induced reversible state where neuromuscular blockade (NMB), hypnosis, and analgesia (jointly denoted by depth of anesthesia - DoA) are guaranteed. This thesis concerns mathematical modeling and feedback control of the effect of the muscle relaxants atracurium and rocuronium, the hypnotic propofol, and the analgesic remifentanil. LÄS MER