Sökning: "Marcus James Graeme Watson Ladds"

Hittade 1 avhandling innehållade orden Marcus James Graeme Watson Ladds.

  1. 1. p53 transcriptional activity as a tool to uncover novel and diverse druggable targets in cancer

    Författare :Marcus James Graeme Watson Ladds; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The transcription factor p53 is one of the most studied tumour suppressors with over 90 000 publications in PubMed referring to the protein. It is also the most frequently mutated gene across all cancer types with around 50% of cancers presenting as mutant p53, and when it is not mutated, it is frequently inactivated to circumvent its tumour suppressor function. LÄS MER