Sökning: "Malin Lindqvist"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Malin Lindqvist.

  1. 1. Pharmacogenetic studies of thiopurines : focus on thiopurine methyltransferase

    Författare :Malin Lindqvist Appell; Michel Eichelbaum; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Pharmacogenetics represents the study ofvariability in drug response due to genetic variations. The thiopurines (6-mercaptopurine, 6-thioguanine and azathioprine) are prodrugs which require metabolic transformation to exert effect. LÄS MER

  3. 2. To tear and to heal : pelvic floor dysfunction and childbirth

    Författare :Malin Huber; Katarina Tunón; Pär Nordin; Karin Strigård; Maria Lindqvist; Kjell Å. Salvesen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pelvic floor disorders; endosonography; dyspareunia; perineum; pain; qualitative research; delivery; Medicine; medicin;

    Sammanfattning : Background: Up to 80% of women are affected by a perineal laceration after their first vaginal birth. An estimated 40–50% of lacerations involve the perineal muscles, and up to 7% are obstetric anal sphincter injuries (OASI). LÄS MER

  4. 3. Essays in Swedish Family Policy

    Författare :Malin Tallås Ahlzén; Anne Boschini; Erik Lindqvist; Lisa Laun; Rita Ginja; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; public economics; labor economics; gender; parental leave; quotas; childcare; cognitive development; Economics; nationalekonomi;

    Sammanfattning : Parental Leave Quotas: Peer Effects and Workplace Related CostsIn this paper, I estimate whether the introduction and expansion of parental leave quotas in Sweden triggered spillovers at the workplace level. Using a regression discontinuity design, I find that the introduction of the quota did not affect the uptake of parental leave of male coworkers. LÄS MER

  5. 4. Coding to cure : NMR and thermodynamic software applied to congenital heart disease research

    Författare :Markus Niklasson; Patrik Lundström; Malin Lindqvist Appell; Björn Wallner; Katja Petzold; Malmendal Anders; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Regardless of scientific field computers have become pivotal tools for data analysis and the field of structural biology is not an exception. Here, computers are the main tools used for tasks including structural calculations of proteins, spectral analysis of nuclear magnetic resonance (NMR) spectroscopy data and fitting mathematical models to data. LÄS MER

  7. 5. Biophysical Characterization of Thiopurine S-Methyltransferase : A Key enzyme in the Effects of Thiopurine Drugs

    Författare :Patricia Wennerstrand; Lars-Göran Mårtensson; Curt Peterson; Malin Lindqvist Appell; Mikael Widersten; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : In the treatment of leukemia and inflammatory bowel disease, thiopurines are commonly used drugs. Thiopurine S-methyltransferase (TPMT) is one of the drug metabolizing enzymes responsible of counteracting the formation of TGNs that will be incorporated into the DNA and RNA synthesis and thus induce apoptosis. LÄS MER