Sökning: "Major histocompatibility complex molecules"
Visar resultat 6 - 10 av 47 avhandlingar innehållade orden Major histocompatibility complex molecules.
6. Immunoecology of the Great Snipe (Gallinago media) : Mate Choice, MHC Variation, and Humoral Immunocompetence in a Lekking Bird
Sammanfattning : At the centre of the vertebrate immune system is a group of proteins called MHC (major histocompatibility complex) molecules. These function in self – non self recognition and activation of the immune defence against intruding parasites and pathogens. LÄS MER
7. Pathogenesis of arthritis in rats : genetic factors and inducing molecules
Sammanfattning : Rheumatoid Arthritis (RA) is a chronic joint disease for which there is presently no cure, possibly because rational design of therapy is hindered by lack of knowledge of disease mechanisms (pathogenesis), and disease causing genetic and inducing factors (etiology). In this thesis, etiopathogenetic clues were sought in experimental arthritis, induced in different rat strains using both specific and nonspecific triggers of the immune system, i. LÄS MER
8. Immune recognition molecules in synaptic plasticity and regeneration of spinal motoneurons
Sammanfattning : This thesis is based on the emerging concept that pattern recognition molecules, originally characterized in the immune system, may be expressed and used by neurons to mediate non-immune functions. In line with this concept, the major histocompatibility complex (MHC) class I and certain complements proteins have been implicated in synaptic plasticity in the developing visual system. LÄS MER
9. The influence of adhesion molecules on binding and protein organization in cell contacts
Sammanfattning : Interactions between immune cells such as T cells and antigen-presenting cells (APCs) are integral for mounting an adaptive immune response. The interaction between the T cell receptor (TCR) and the antigen-presenting major histocompatibility complex (pMHC) on a contacting T cell and APC, is widely accepted to be the key interaction. LÄS MER
10. Expression of stimulatory and inhibitory molecules in interactions between natural killer cells neurons
Sammanfattning : Natural killer (NK) cells are important effector cells of the innate and the early induced immune defense. In the nervous system they appear early during inflammation and have been ascribed a role in clearance of certain viral infections from the brain. NK cells are regulated by multiple signals transmitted via inhibitory and stimulatory receptors. LÄS MER