Sökning: "Magnus Artursson"

Hittade 3 avhandlingar innehållade orden Magnus Artursson.

  1. 1. Bebyggelse och samhällsstruktur. Södra och mellersta Skandinavien under senneolitikum och bronsålder 2300-500 f. Kr

    Författare :Magnus Artursson; Göteborgs universitet; []
    Nyckelord :HUMANIORA; HUMANITIES;

    Sammanfattning : The main focus of this thesis is a comparative study of the structure and organisation of Late Neolithic and Bronze Age (2300-500 BC) settlements across the southern and middle part of Scandinavia. Variation in size and associations of long-houses and farmsteads are used to analyse economic, social and political complexity. LÄS MER

  3. 2. Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

    Författare :Magnus Ölander; Per Artursson; Pär Matsson; Edward L. LeCluyse; Volker Lauschke; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; drug disposition; ADMET; drug transport; drug metabolism; hepatotoxicity; small intestine; liver; caco-2; human hepatocytes; cryopreservation; apoptosis; liver zonation; non-parenchymal cells; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : To reach the bloodstream, an orally administered drug must be absorbed through the small intestine and avoid extensive clearance in the liver. Estimating these parameters in vitro is therefore important in drug discovery and development. LÄS MER

  4. 3. Chitosan Polyplexes as Non-Viral Gene Delivery Systems : Structure-Property Relationships and In Vivo Efficiency

    Författare :Magnus Köping-Höggård; Per Artursson; Jean-Paul Behr; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; gene therapy; gene delivery; non-viral; polyplex; chitosan; chitosan oligomers; polyethylenimine; plasmid DNA; lung; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : The subject of this thesis was to develop and optimize delivery systems for plasmid DNA (pDNA) based on biocompatible polymers, in particular chitosan, suitable for non-viral gene therapy. At the onset of this thesis, studies had reported conflicting results on the efficiency of chitosan-based gene delivery systems. LÄS MER