Sökning: "Madelene Dahlgren"

Hittade 1 avhandling innehållade orden Madelene Dahlgren.

1. 1. Regulation of the germinal center response by T follicular helper cells and type I interferons

   Författare :Madelene Dahlgren; Adaptivt immunförsvar; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Germinal Center; T follicular helper cell; type I interferon; dendritic cell; adjuvant; differentiation; IgG;

   Sammanfattning : The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to B cell follicles. LÄS MER