Sökning: "Macrophages"

Visar resultat 6 - 10 av 743 avhandlingar innehållade ordet Macrophages.

  1. 6. Molecular targets for glucocorticoids in macrophages: cytosolic phospholipase A2 and cytokine formation

    Författare :Karin Gewert; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; Pharmacological sciences; signal transduction; dexamethasone; cytosolic phospholipase A2; glucocorticoids; macrophages; protein kinase C; mitogen-activated protein kinases; TNF-alpha; IL-1beta; protein phosphatases; okadaic acid; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : The aim of this investigation has been to study mechanisms by which glucocorticoids inhibit inflammatory processes in vitro. Type IV cytosolic 85 kDa phospholipase A2 (cPLA2) is an important modulator of inflammatory responses that is present in macrophages as well as in other cell types. LÄS MER

  3. 7. Signalling to Activation of Cytosolic Phospholipase A2 and Arachidonate Release in Macrophages

    Författare :Gösta Hiller; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; dexamethasone; macrophages; phospholipase C; phosphatidylinositol 3-kinase; mitogen-activated protein kinases; cytosolic phospholipase A2; arachidonic acid; Histology; cytochemistry; histokemi; cytokemi; tissue culture; Histologi; vävnadskultur; histochemistry;

    Sammanfattning : Eicosanoids include prostaglandins, thromboxanes and leukotrienes, which are arachidonic acid oxygenation products. These lipids make important contributions to the signs and symptoms of inflammatory diseases. LÄS MER

  4. 8. Macrophages, Nitric oxide synthases and Heme oxygenases: possible roles during peripheral nerve regeneration

    Författare :Sofia Magnusson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; satellite cells; peripheral ganglia; cell signalling; nerve regeneration; heme oxygenase; Macrophages; nitric oxide synthase; Animal physiology; Djurfysiologi;

    Sammanfattning : The purpose of this study was to investigate the suggestions that macrophages, and the systems generating nitric oxide (NO) and carbon monoxide (CO), i.e. nitric oxide synthases (NOS) and heme oxygenases (HO), could be important for peripheral nerve regeneration. LÄS MER

  5. 9. On macrophage contributions to tissue homeostasis : New insights on pancreas development and healing of ischemic injury

    Författare :Carmen Herrera Hidalgo; Mia Phillipson; Andrés Hidalgo; Uppsala universitet; []
    Nyckelord :macrophages; islets of Langerhans; β cell function; postnatal β cell maturation; hindlimb ischemia; blood flow regulation; mural cells; vessel pruning; diabetes mellitus; ischemic diseases;

    Sammanfattning : Besides providing host defence against innumerable threats, macrophages display additional key functions for preservation of tissue homeostasis. This thesis includes four studies that explore novel macrophage functions in both the development of islets of Langerhans and healing of ischemic injury in mice. LÄS MER

  7. 10. Macrophage programming and host responses to bacterial infection

    Författare :Xiao Wang; Hong Sjölinder; Martin Rottenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Macrophages; meningococci; mycobacteria; NhhA; CD46; cytokines; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. LÄS MER