Sökning: "Macrophages migration"

Visar resultat 1 - 5 av 72 avhandlingar innehållade orden Macrophages migration.

  1. 1. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer

    Författare :Catharina Hagerling; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Wnt5a; E-cadherin; B-catenin; migration; invasion; turnor associated macrophages; CD163; CD68; turnor stroma;

    Sammanfattning : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. LÄS MER

  3. 2. The effects of plasminogen deficiency on the healing of tympanic membrane perforations

    Författare :Annika Hansson; Sten Hellström; Diana Berggren; Tor Ny; Magnus von Unge; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tympanic membrane; macrophages; neutrophils; fibrin ogen ; inflammation; keratinocyte migration; wound healing; uPA; tPA; in vitro; Otorhinolaryngology; Otorhinolaryngologi;

    Sammanfattning : The healing of tympanic membrane (TM) perforations is a complex wound healing process including inflammation, migration of keratinocytes and tissue remodelling. Most TM perforations in human heal spontaneously, however some perforations become chronic, and the reason to why is still largely unknown. LÄS MER

  4. 3. Crosstalk between colorectal cancer cells and tumour-associated macrophages

    Författare :Yuan Zhang; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD47; tumour-associated macrophage; matrix metalloproteinase; cell migration; colon cancer;

    Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. LÄS MER

  5. 4. The effect of hypoxia on macrophage proteoglycans: potential role in atherosclerosis

    Författare :Annika Asplund; Göteborgs universitet; []
    Nyckelord :atherosclerosis; proteoglycans; glycosaminoglycans; macrophages; hypoxia; hypoxia-inducible transcription factor; LDL binding; cell motility;

    Sammanfattning : A critical step in the development of atherosclerotic lesions appears to be the retention of low density lipoproteins (LDL) in the arterial wall, mediated by negatively charged proteoglycans (PG). Retained LDL is susceptible to modification and uptake by resident macrophages that are found in hypoxic sites in atherosclerotic lesions (with oxygen levels below 1%). LÄS MER

  7. 5. Acute pancreatitis, from local defense to remote organ injury

    Författare :Hamid Akbarshahi; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; heparan sulfate; damage associated molecular patterns; toll-like receptor4; MyD88; IRF-3; acute lung injury; macrophages; transforming growth factor-beta; Smad;

    Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung injury (ALI). LÄS MER