Sökning: "Macromolecular chemistry"

Visar resultat 16 - 20 av 45 avhandlingar innehållade orden Macromolecular chemistry.

  1. 16. From Macromolecular Design to Supramolecular Self-assembly

    Författare :Lidija Glavas; Ann-Christine Albertsson; Karin Odelius; Matthew Becker; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Self-assembly; micelles; core crystallinity; cyclic polypeptides; electroactivity; redox-responsiveness; triggered dissociation; loading; release; N-carboxyanhydride polymerization; polyesters; poly ε-decalactone ; Självorganisation; miceller; kärnkristallinitet; cykliska polypeptider; elektroaktivitet; tidsberoende dissociation; inkapsling; frisläppning; N-karboxyanhydrid polymerisation; polyestrar; poly ε-dekalakton ; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Advancements in drug delivery have enabled a wider array of prevention, control and treatment of diseases such as cancer. Drug delivery systems have the possibility of encapsulating drugs with low solubility, delivering them to specific locations in the body as well as obtaining a controlled and sustained drug release. LÄS MER

  3. 17. Biophysical chemistry of the ALS-associated protein SOD1 : Implications for folding, aggregation and in-cell behaviour

    Författare :Fan Yang; Mikael Oliveberg; Per Jemth; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SOD1 ALS folding in-cell NMR aggregation; Biochemistry; biokemi;

    Sammanfattning : Biophysical chemistry deals with the structural behavior, properties and molecular function of biological macromolecules. A long-standing challenge is here to establish how these macromolecular features change upon transfer from simplified conditions in vitro to the crowded and molecularly complex environment of live cells. LÄS MER

  4. 18. Advanced NMR techniques for structural elucidation in medicinal chemistry

    Författare :Hermina Wieske; Máté Erdélyi; Mikael Akke; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The nuclear Overhauser effect (NOE) is an NMR phenomenon that can reveal spatial proximity between two atoms. It has found applications in organic chemistry and structural biology including natural product chemistry, organic synthesis, medicinal chemistry, macromolecular structure elucidation and protein-ligand interactions. LÄS MER

  5. 19. Interpolymer complexation of a polymer brush

    Författare :John Andersson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; functional materials; macromolecular gating; Interpolymer complex; nanopores; polymer brush; pH responsive;

    Sammanfattning : Controllable macromolecular gating between nanoscopic compartments is of high interest for single molecule studies of biological macromolecules. By definition, a good macromolecular gate should completely stop biomolecules, such as proteins, from crossing between compartments in its closed state while letting them pass in its open state. LÄS MER

  7. 20. Protein structure dynamics and interplay : by single-particle electron microscopy

    Författare :Hans Elmlund; Hans Hebert; José Maria Carazo; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biophysics; biochemistry; molecular; Biophysical chemistry; Biofysikalisk kemi;

    Sammanfattning : Single-particle cryo-electron microscopy (cryo-EM) is a method capable of obtaining information about the structural organization and dynamics of large macromolecular assemblies. In the late nineties, the method was suggested to have the potential of generating “atomic resolution” reconstructions of particles above a certain mass. LÄS MER