Sökning: "MUC3"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet MUC3.

1. 1. The Relationship between Transmembrane Mucins, Ion Channels and PDZ Adaptor Proteins in the Small Intestine

   Författare :Thaher Pelaseyed; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucin; MUC3; MUC17; SEA; PDZK1; GOPC; CFTR; NHE3;

   Sammanfattning : The human body is continuously exposed to challenges from the surrounding world. In analogy with the skin, mucus is a well-organized and highly regulated barrier composed of polymeric and O-glycosylated mucins that protects luminal organs such as the gastrointestinal tracts from the outer milieu. LÄS MER

3. 2. Mucins, Cystic Fibrosis and PDZ protein interactions

   Författare :Emily Malmberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucin; PDZ; transmembrane; MUC1; Cystic Fibrosis; clathrin; CFTR; PDZK1; Bcr; endocytosis; MUC17;

   Sammanfattning : Cystic Fibrosis (CF) is caused and characterized by mutations in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. The dominating feature of the disease is mucus accumulation on mucosal surfaces, but no direct functional connection between mucus and CFTR is known. LÄS MER

4. 3. Evolution of Transmembrane and Gel-forming Mucins Studied with Bioinformatic Methods

   Författare :Tiange Lang; Göteborgs universitet; []
   Nyckelord :;

   Sammanfattning : All mucosal membranes of the body are covered by mucus, largely made up of the family of large glycoproteins called mucins. These are instrumental for the protection of the underlying epithelia and involved in the pathogenesis of many diseases in the lungs and the intestine. LÄS MER

5. 4. Defence capabilities of human intestinal epithelial cells

   Författare :Anna Fahlgren; Sten Hammarström; Marie-Louise Hammarström; Gudmundur Gudmundsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; intestine; mucosa; epithelium; antimicrobial; defensins; glycocalyx; ulcerative colitis; Crohn´s disease; celiac disease; Immunologi; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : The epithelial cells lining the intestinal mucosa separate the underlying tissue from components of the intestinal lumen. Innate immunity mediated by intestinal epithelial cells (IECs) provides rapid protective functions against microorganisms. Innate immunity also participates in orchestrating adaptive immunity. LÄS MER

7. 5. Human intestinal epithelial cells in innate immunity : interactions with normal microbiota and pathogenic bacteria

   Författare :Gangwei Ou; Sten Hammarström; Marie-Louise Hammarström; Agnes Wold; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; immunologi; Immunology;

   Sammanfattning : Rod-shaped bacteria were previously shown to be associated with the small intestinal epithelium of children with celiac disease (CD). Using culture-dependent and independent methods, we characterized the microbiota of small intestine in children with CD and controls. The normal microbiota constitutes an unique organ-specific biofilm. LÄS MER