Sökning: "MSH2"
Visar resultat 11 - 13 av 13 avhandlingar innehållade ordet MSH2.
11. Mismatch repair deficiency in colorectal cancer : prognosis and prediction for basic treatment strategies
Sammanfattning : Colorectal cancer (CRC) remains a significant healthcare problem worldwide, being the third most common cancer and the fourth most frequent cause of cancer death. Environmental and dietary factors such as alcohol abuse, cigarette smoking, and genetic predisposition seem to constitute the main aetiologies. LÄS MER
12. Improving endometrial carcinoma diagnostics
Sammanfattning : Endometrial carcinoma is the most common gynecological malignancy and greatly affects global disease burden. Despite it being among the most common cancers it is relatively understudied and until recently poorly understood. LÄS MER
13. Tools and pipelines for interpreting the impacts of genetic variants
Sammanfattning : Next generation sequencing (NGS) methods have been widely used for diagnosis. As time and cost of sequencing has reduced sharply during the last decade, genome and exome-wide sequencing have increasingly been used. LÄS MER