Sökning: "MS health"

Visar resultat 21 - 25 av 344 avhandlingar innehållade orden MS health.

  1. 21. Piperaquine - Bioanalys, drug metabolism and pharmacokinetics

    Författare :Joel Tärning; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Piperaquine; malaria; Plasmodium falciparum; antimalarials; ACT; pharmacokinetics; NONMEM; population pharmacokinetics; NCA; bioavailability; enterohepatic circulation; metabolism; metabolites; animal models; bioanalysis; regression models; validation; HPLC; LC-MS MS; H-NMR; FTICR-MS;

    Sammanfattning : Malaria is one of the most abundant parasitic diseases in the world affecting many of the poorest economies. The estimated prevalence is 300 to 700 million clinical episodes each year with up to 3 million deaths. LÄS MER

  3. 22. Chronic sorrow and quality of life in patients with multiple sclerosis

    Författare :Ann-Kristin Isaksson; Gerd Ahlström; Lars-Gunnar Gunnarsson; Siv Söderberg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; illness experience; diagnosis experience; impairment; health-related quality of life; subjective quality of life; immunological treatment; chronic sorrow; depression; managing chronic illness; content analysis; well-being; Caring sciences; Vårdvetenskap; Vårdvetenskap; Nursing Science;

    Sammanfattning : The overall aim of this thesis was to increase our understanding and knowledge of patients’ experiences of living with multiple sclerosis (MS). A mixed-method design was used, including both qualitative and quantitative methods. LÄS MER

  4. 23. Studies of the Biology of Intrathecal Treatment in Progressive MS

    Författare :Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

    Sammanfattning : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. LÄS MER

  5. 24. Regulation of CNS inflammation upon T cell interaction with CNS resident cells

    Författare :Ingrid Teige; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurofysiologi; neuropsykologi; Neurologi; neurophysiology; neuron; glia; CNS; T cell; cytokine; immunoregulation; MS; EAE;

    Sammanfattning : Multiple Sclerosis (MS), is a neurologic, autoimmune disease characterized by CNS immune cell infiltration and demyelination. To experimentally study MS, we have utilized the mouse model Experimental Autoimmune Encephalomyelitis (EAE). EAE is induced through immunization with myelin antigens, which elicits an autoreactive Th1 cell response. LÄS MER

  7. 25. From disease to genes in animal models of rheumatoid arthritis and multiple sclerosis

    Författare :Therese Lindvall; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mice; animal models; autoimmunity; CIA; EAE; RA; MS;

    Sammanfattning : Rheumatoid arthritis (RA) and multiple sclerosis (MS) are complex inflammatory autoimmune diseases. The aetiology is largely unknown but the risk of developing disease is dependent on both genetic and environmental factors. LÄS MER