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Visar resultat 1 - 5 av 13 avhandlingar som matchar ovanstående sökkriterier.
1. Bowel irradiation: the effects on inflammation and matrix-metalloproteinases
Sammanfattning : Background and aims: Radiotherapy is a valid treatment in cancer multimodal management but it is affected by severe systemic and local side effects. A murine small bowel model was used for the investigation of inflammatory features and apoptosis of local radiotherapy. LÄS MER
2. Molecular determinants of disease severity in urinary tract infection
Sammanfattning : In the urinary tract, Escherichia coli infection may result in life-threatening disease, or asymptomatic bacterial carriage, comparable to bacterial commensalism in the gut. Pathogenic strains trigger a disease provoking host response which differs depending on the infected organ. LÄS MER
3. Towards surgical use of matrix metalloproteinase biology
Sammanfattning : Matrix metalloproteinases (MMPs), such as collagenases, are a family of enzymes capable of degrading most constituents of the extracellular matrix. MMPs are thought to be involved in the aetiopathogenesis of tendon rupture. Additionally, failure of healing has in some instances been associated with elevated levels of MMPs. LÄS MER
4. Matrix degrading proteases in vascular disease
Sammanfattning : Diverse processes of vascular disease including lesion growth, plaque rupture and abdominal aortic aneurysm formation are influenced by protease expression. Arteries undergo compensatory remodelling when the mechanical forces that are imposed on them are altered. LÄS MER
5. Identification of Tumor Cell- and Stroma Derived Biomarkers of Treatment Response in Head and Neck Cancer
Sammanfattning : Head and neck squamous cell carcinoma (HNSCC) poses a major health problem in the world with approximately 600 000 new cases yearly. Treatment resistance is a major problem within this patient group and despite advances in treatment strategies the overall survival rate has unfortunately not increased. LÄS MER