Sökning: "MITOCHONDRIAL-DNA"

Visar resultat 1 - 5 av 116 avhandlingar innehållade ordet MITOCHONDRIAL-DNA.

  1. 1. Mitochondrial DNA : analysis of the control region in forensic and population genetic studies

    Författare :Peter Savolainen; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mitochondrial DNA; control region; tandem repeats; D-loop; homoplasmy; hair; forensic; microsatellites; evolution; DNA sequencing; PCR; domestic dog; wolf; Bioengineering; Bioteknik;

    Sammanfattning : .... LÄS MER

  3. 2. Mitochondrial DNA in Sensitive Forensic Analysis

    Författare :Martina Nilsson; Marie Allen; Ulf Gyllensten; Antti Sajantila; Uppsala universitet; []
    Nyckelord :Genetics; Forensic genetics; Mitochondrial DNA; HVI HVII; Nuclear DNA; Quantification; Real-time PCR; Immobilised SSO probe assay; Pyrosequencing; Discrimination power; Coding region; Mixtures; Genetik;

    Sammanfattning : Genetic profiling is commonly performed on the autosomes using multiple DNA markers. Although routine forensic DNA analysis is robust and based on reliable technologies, samples with degraded or limited amounts of DNA often fail. In these cases, the analysis of mitochondrial DNA (mtDNA) can be very valuable due to the high copy number per cell. LÄS MER

  4. 3. The consequences of DNA lesions for mitochondrial DNA maintenance

    Författare :Josefin M. E. Forslund; Sjoerd Wanrooij; Nasim Sabouri; Erik Johansson; Claes Gustafsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitochondria; mitochondrial DNA; DNA replication; DNA lesions; DNA polymerase γ; ribonucleotide incorporation; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Eukaryotic cells have their own energy-producing organelles called mitochondria. The energy is stored in the adenosine triphosphate (ATP) molecule and is produced via the oxidative phosphorylation process inside the mitochondria. Thirteen of the essential proteins required for this process are encoded on the mitochondrial DNA (mtDNA). LÄS MER

  5. 4. Application of Mitochondrial DNA Analysis in Contemporary and Historical Samples

    Författare :Maria Lembring; Marie Allen; Niels Morling; Uppsala universitet; []
    Nyckelord :Forensic genetics; Mitochondrial DNA; HVI HVII; Population database; Haplotype; Haplogroup; Ancient DNA; Historical DNA samples; skeletal remains; Vasa museum; Medieval samples; Copernicus; Göring; Genetik; Genetics;

    Sammanfattning : The mitochondrion is a tiny organelle that is the power supplier of the cell and vital to the functioning of the body organs. Additionally it contains a small circular genome of about 16 kb, present in many copies which makes the mitochondrial DNA more viable than nuclear DNA. LÄS MER

  7. 5. Molecular insights into mitochondrial DNA replication

    Författare :Javier Miralles Fusté; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondria are organelles found in eukaryotic cells. These organelles produce most of the adenosine triphosphate that cells use as a source of energy. Mitochondria contain their own genomic material, a circular DNA genome (mtDNA) that encodes subunits of the respiratory chain complexes and RNA components needed for mitochondrial translation. LÄS MER