Sökning: "MIB"

Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet MIB.

  1. 1. Clinical and molecuar studies of papillary thyroid carcinoma : with an emphasis on prognostic factors

    Författare :Petra Kjellman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Papillary thyroid carcinoma; MIB-1; RET-proto-oncogene; RET PTC; CGH; prognosis;

    Sammanfattning : Thyroid cancer accounts for approximately 1% of all cancers reported. In Sweden 45/100, 000 inhabitants annually present with thyroid carcinoma. There are four different variants of thyroid carcinoma: papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, medullary thyroid carcinoma and anaplastic thyroid carcinoma. LÄS MER

  3. 2. Endometrial carcinoma : prognostic factors and protein expression profiling

    Författare :Caroline Lundgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endometrial carcinoma; prognosis; DNA ploidy; MIB-1; p53; laminin-5 72 chain; 2DE;

    Sammanfattning : Endometrial carcinoma is the most common gynaecological cancer in the western world. It is usually diagnosed at an early stage since it presents with irregular vaginal bleeding when the tumour is still limited to the uterus and the prognosis is generally favourable. LÄS MER

  4. 3. Tumor progression in melanocytic lesions : biological and diagnostic implications

    Författare :Lena Kanter-Lewensohn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :melanocytic tumors; MIB-1; Bcl-2; IGF-1R. p27; cyclins; cdks and Tamoxifen;

    Sammanfattning : Cutaneous malignant melanoma has an annual incidence of 5% in Sweden, with about 1500 cases diagnosed yearly. In routine histopathology there are diagnostic difficulties in the analysis of pigmented lesions. LÄS MER

  5. 4. Prognostic markers in breast cancer associated with cell cycle control, proliferation and angiogenesis

    Författare :Thomas Lindahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; TP53; VEGF; cyclin E; Ki-67; MIB-1; p21; MDM-2; survival; prognostic markers;

    Sammanfattning : This thesis focuses on potential prognostic molecular breast cancer markers which are related to angiogenesis, proliferation or cell cycle control. A common denominator for all of the investigated markers in the thesis is either hypothesized or previously reported association with the tumor suppressor gene TP53. LÄS MER

  7. 5. In search of diagnostic and prognostic markers for thyroid cancer : a proteomics approach

    Författare :Anastasios Sofiadis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Thyroid tumors; thyroid proteomics; S100A6; MIB-1; 2DE; MALDI-TOF-MS; SELDI-TOF-MS; protein pre-fractionation;

    Sammanfattning : Early diagnosis of cancer can influence the therapeutic strategy increasing the chances of cure or, at least, prolonged survival. It is equally important to be able to detect prognostic signs, i.e. tumor features that characterize its behavior. LÄS MER