Sökning: "MEDICIN Kemi"

Visar resultat 1 - 5 av 592 avhandlingar innehållade orden MEDICIN Kemi.

  1. 1. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

    Detta är en avhandling från Gothenburg : Chalmers tekniska högskola

    Författare :Lukas Boge; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hexosome; antimicrobial peptide; cubosome; proteolysis; AMP; liquid crystalline nanoparticles; glycerol monooleate; Liquid crystals;

    Sammanfattning : The development of antimicrobial resistance is a great challenge within the health sector around the world. The demand for new efficient treatments is alarming in order to treat various bacterial infections in the near future. Antimicrobial peptides (AMPs) are a group of novel antibiotics that have gain more and more attraction the past decade. LÄS MER

  2. 2. Pilicides and Curlicides Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence

    Detta är en avhandling från Umeå : Umeå universitet, Kemiska Institutionen

    Författare :Erik Chorell; Fredrik Almqvist; Stephen Hanessian; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pilicide; curlicide; anti-virulence; chaperone usher pathway; antibacterial; pili; curli; Escherichia coli; biofilm inhibitor; 2-pyridone; peptidomimetic; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry Bioorganic chemistry; NATURVETENSKAP Kemi Organisk kemi Bioorganisk kemi; NATURAL SCIENCES Chemistry Organic chemistry Pharmaceutical chemistry; NATURVETENSKAP Kemi Organisk kemi Läkemedelskemi; NATURAL SCIENCES Chemistry Organic chemistry Organic synthesis; NATURVETENSKAP Kemi Organisk kemi Organisk syntes; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar; Biorganic Chemistry; bioorganisk kemi; Infectious Diseases; infektionssjukdomar; datorlingvistik; computational linguistics; organisk kemi; Organic Chemistry;

    Sammanfattning : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. LÄS MER

  3. 3. Molecular Imaging of Diabetic Kidney Tissue and Binding Studies of Proinsulin C-peptide

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Lina Lindfors; Jan Kihlberg; Ingela Lanekoff; Fredrik Almqvist; [2020]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Diabetic kidney disease; Proinsulin C-peptide; GPR146; Mass spectrometry imaging; nano-DESI; Kemi; Chemistry;

    Sammanfattning : Diabetic kidney disease is a serious complication of diabetes with a complex and incompletely understood pathology. In this work, the molecular changes in diabetic rat kidneys at a very early disease stage were studied using nanospray desorption electrospray ionisation mass spectrometry imaging. LÄS MER

  4. 4. Creating Ultrafast Biosensors for Neuroscience

    Detta är en avhandling från Gothenburg : Chalmers tekniska högskola

    Författare :Yuanmo Wang; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantification; glucose; choline oxidase; gold nanoparticles; enzyme monolayer; enzymatic activity; Biosensor; adsorption; brain slice; enzyme stability; acetylcholine esterase; artificial cell; exocytosis; glucose oxidase; deformation; glutamate; glutamate oxidase; acetylcholine; amperometry;

    Sammanfattning : Neuronal communication is the basis for all our brain function and relies on regulated exocytosis, a cell function that involves release of quantal amounts of neurotransmitters into the gap space between interconnected neurons to serve as chemical signals. To study exocytosis, which is a fast process that occurs on the timescale of sub-milliseconds to milliseconds, a toolbox of analytical methods has been developed where the electrochemical based techniques offer quantitative and sufficient high temporal recording speed. LÄS MER

  5. 5. Rational design and synthesis of protease inhibitors : targeting HIV-1, Malaria Plm I and II and Hepatitis C virus NS3 proteases

    Detta är en avhandling från Stockholm : Stockholm University

    Författare :Karin Oscarsson; [2002]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER