Sökning: "MAPK signaling"

Visar resultat 16 - 20 av 120 avhandlingar innehållade orden MAPK signaling.

  1. 16. On Some Problems in Systems Biology and Geometric Flows

    Författare :Tobias Gebäck; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; system biology; MAPK signaling pathways; reaction-diffusion equation; Immersed Interface Method; Boolean grids; curvature flows; viscosity solutions; convolutionthresholding schemes; system biology;

    Sammanfattning : .... LÄS MER

  3. 17. Proinsulin C-peptide : membrane interactions and intracellular signaling

    Författare :Zhihui Zhong; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human renal tubular cell; intracellular signal transduction; ERK1 2; JNK; Na ; K -A TPase; G-protein coupled receptor.;

    Sammanfattning : In the past decade, new evidence has emerged of a physiological role for C-peptide. C-peptide replacement improves renal and nerve function and augments regional blood flow in type I diabetic patients. LÄS MER

  4. 18. JNK/c-Jun Signaling and Peripheral Nerve Regeneration

    Författare :Charlotta Lindwall; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neuropsykologi; neurofysiologi; neurophysiology; Neurologi; neuropsychology; Neurology; Djurfysiologi; Animal physiology; JNK; signal transduction; nerve regeneration;

    Sammanfattning : The events associated with axonal injury in the peripheral nervous system (PNS) have been described in detail. However, the molecular mechanisms underlying the regenerative response, or neuronal cell death, following axonal injury are poorly understood. LÄS MER

  5. 19. Elucidation of pro-apoptotic signaling induced by cisplatin

    Författare :Aleksandra Mandic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Keywords: Cisplatin; apoptosis; signal transduction; Bak; calpain; endoplasmic reticulum;

    Sammanfattning : A major clinical problem regarding treatment of malignant tumors with anticancer drugs is inherent or acquired resistance to therapy. One factor contributing to drug resistance of cancer cells is failure to undergo apoptosis. LÄS MER

  7. 20. Interleukin-6 Signaling Pathways in Human Vascular Endothelial Cells : Molecular Mechanisms and Associations to Atherosclerosis

    Författare :Mulugeta Melkie Zegeye; Liza Ljungberg; Allan Sirsjö; Ashok K Kumawat; Magnus Grenegård; Stefan Rose-John; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HUVECs; Angiogenesis; Laminins; Transmigration; Biomarker; Cytokine; Inflammation; Myocardial infarction;

    Sammanfattning : Interleukin-6 is pleotropic cytokine produced by several types of cells including endothelial cells (ECs). IL-6 acts on target cells via two major signaling mechanisms known as classic signaling and trans-signaling. LÄS MER