Sökning: "MAD"

Visar resultat 6 - 10 av 33 avhandlingar innehållade ordet MAD.

1. 6. Regulation and function of the Mad/Max/Myc network during neuronal and hematopoietic differentiation

   Författare :Anne Hultquist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Myc; Mad1; neuroblastoma; hematopoiesis; phorbol ester; retinoic acid; interferon-g; TGF-b; differentiation.; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : The Mad/Max/Myc transcription factor network takes part in the control of vital cellular functions such as growth, proliferation, differentiation and apoptosis. Dimerization with the protein Max is necessary for the Myc-family of oncoproteins and their antagonists, the Mad-family proteins, to regulate target genes and carry out their intended functions. LÄS MER

3. 7. Am I mad, bad or dangerous? : A novel intervention approach for unwanted intrusive thoughts

   Författare :Klara Olofsdotter Lauri; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Unwanted intrusive thoughts (UITs) containing unacceptable and taboo themes is regarded as a common and, for most, transient cognitive phenomenon. However, these thoughts can become so frequent and distressing that the individual’s daily functioning and well-being are impaired, even to the extent that the individual fulfils the criteria for obsessivecompulsive disorder (OCD). LÄS MER

4. 8. Health Information Systems Interoperability: Towards a Managing as Designing Approach

   Författare :Grace Kobusinge; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Health Information Systems HIS ; Managing as Designing MaD ; Interoperability Implementation; Contextual Understanding; Context of Interaction;

   Sammanfattning : Integrated digital healthcare systems promise improved quality public healthcare and patient continued care among others. However, these have been hampered by various challenges including limited data exchanges between health information systems (HIS) and inadequate collaboration among healthcare centers and healthcare professionals. LÄS MER

5. 9. “Lasciatemi morire” o farò “La Finta Pazza”: Embodying Vocal Nothingness on Stage in Italian and French 17th Century Operatic Laments and Mad Scenes

   Författare :Elisabeth Belgrano; Göteborgs universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; voice; singing; nothingness; je-ne-sais-quoi; 17th century opera; pure voice; lamentation; madness; passions; emotions; nightingale; transformation; ornamentation; observation; improvisation; interpretation; vocal expression; embodiment; creative process; performance; repetition; movement; inner images; artistic research;

   Sammanfattning : This music research drama thesis explores and presents a singer’s artistic research process from the first meeting with a musical score until the first steps of the performance on stage. The aim has been to define and formulate an understanding in sound as well as in words around the concept of pure voice in relation to the performance of 17th century vocal music from a 21st century singer’s practice-based perspective with reference to theories on nothingness, the role of the 17th century female singer, ornamentation (over-vocalization) and the singing of the nightingale. LÄS MER

7. 10. Safety limit estimation for cataract induced by ultraviolet radiation

   Författare :Xiuqin Dong; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ultraviolet radiation UVR ; Sprague-Dawley rat; cataract; light scattering; doseresponse function; maximum acceptable dose MAD ; maximum tolerable dose MTD ; in vivo; in vitro; age.;

   Sammanfattning : Background: Ultraviolet radiation (UVR) is considered one of the major risk factors for agerelated cataract. UVR-induced cataract follows a continuous dose-response function. LÄS MER