Sökning: "MAD"

Visar resultat 1 - 5 av 27 avhandlingar innehållade ordet MAD.

  1. 1. Mad Pursuits : Therapeutic Narration in Postwar American Fiction

    Författare :Gwendolyn Haevens; David Associate Professor; Leerom Medovoi; Uppsala universitet; []
    Nyckelord :HUMANITIES; HUMANIORA; early postwar American fiction; popular psychoanalysis; narrative therapy; narrative identity; narrative theory; representation of identity; script theory; therapeutic narration; fugitive selves; J.D. Salinger; Ralph Ellison; Sylvia Plath; English; Engelska;

    Sammanfattning : Mad Pursuits: Therapeutic Narration in Postwar American Fiction examines three mid-century American novels—J.D. Salinger’s The Catcher in the Rye (1951), Ralph Ellison’s Invisible Man (1952), and Sylvia Plath’s The Bell Jar (1963)—in relation to the rise and popularization of psychoanalytic theory in America. LÄS MER

  2. 2. bHLH transcription factors in differentiating neuroblastoma cells

    Författare :Anna Grynfeld; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bHLH; Neuroblastoma; HES-1; HASH-1; N-Myc; differentiation; Mad; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Neuroblastoma is a tumor of the sympathetic nervous system, and arises during early childhood. The tumor is highly heterogeneous and evidence, such as expression of genes normally only expressed during embryonic and fetal stages, suggests that the tumor is of embryonic origin and that the tumor arises as a consequence of perturbed differentiation during the development of the sympathetic nervous system. LÄS MER

  3. 3. Structural Studies of Three Glycosidases

    Författare :Anna Larsson; Alwyn Jones; Janet Smith; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; glycosidase; dextranase; mannanase; endoglucanase; SeMet; MAD; crystal structure; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : Glycosidases hydrolyse the glycosidic bond in carbohydrates. Structural studies of three glycosidases with different substrate specificities are presented in this work.Dextranase catalyzes the hydrolysis of α-1,6-glycosidic linkage in dextran polymers. LÄS MER

  4. 4. Roles of Myc and Mad in cell cycle and apoptosis

    Författare :Ami Albihn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Myc; Mad; cell cycle; apoptosis; differentiation; tumorigenesis; chemotherapy;

    Sammanfattning : The Myc network proteins are key mediators in regulation of cell growth, differentiation and apoptosis. They are basic region hehx-loop-helix/leucine zipper (bHLH/Zip) transcription factors that require hetero-dimerization with Max for specific DNA binding Mad family members are expressed primarily in differentiated tissues where they recruit histone deacetylase complexes via the mSin3 interaction domain (SID) to repress transcription of target genes and prevent cell growth In contrast, members of the Myc family activate target gene transcription by recruitment of histone acetyltransferases to their transcriptional activation domain (TAD), inducing proliferation and S phase entry. LÄS MER

  5. 5. The Birth of a Heruka : How Sangs rgyas rgyal mtshan became gTsang smyon Heruka: A Study of a Mad Yogin

    Författare :Stefan Larsson; Per-Arne Berglie; Erik af Edholm; Hanna Havnevik; Stockholms universitet; []
    Nyckelord :HUMANITIES; HUMANIORA; HUMANIORA; HUMANITIES; Tibetan Buddhism; Tantric Buddhism; bKa’ brgyud tradition; gTsang smyon Heruka 1452–1507 ; mad yogin rnal ’byor smyon pa ; hagiography rnam thar ; “disciplined conduct” brtul zhugs spyod pa ; History of religion; Religionshistoria; religionshistoria; History of Religion;

    Sammanfattning : gTsang smyon Heruka (1452–1507) is one of Tibet’s most famous mad yogins. The mad yogins represent a relatively unknown aspect of Tibetan Buddhism that flourished in the 15th and 16th centuries. LÄS MER