Sökning: "M1-protein"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet M1-protein.

  1. 1. Bacterial virulence or exorbitant host response? On innate immunity against the streptococcal M1 protein

    Författare :Sandra Persson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skin infection; Streptococcus pyogenes; M1 protein; Innate Immunity; Host response; Virulence factor; Neutrophil recruitment; Heparin-binding protein HBP ; Leptospirosis;

    Sammanfattning : Bacterial infection is inevitable throughout a lifetime. What differs between mild andserious infections is the pathogen responsible and how the host immune systemresponds to it. A fundamental role to prevent infection is a proper physical barrier such as the skin and mucosa. LÄS MER

  3. 2. Actions of Antimicrobial Peptides and Bacterial Components in Inflammation

    Författare :Thorgerdur Sigurdardottir; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; LL-37; M1 protein; S. pyogenes; Toll-like receptors; phenylephrine; nitr1c oxide; antimicrobial peptides;

    Sammanfattning : Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response contributing to septic shock. LÄS MER

  4. 3. Bacterial components and sepsis: Group A streptocci, endotoxin and the vascular wall

    Författare :Viveka Björck; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; group A streptococci; endotoxin; LPS; vascular wall; hyporesponiveness; NO; TLR; cytokines; albumin; M1-protein; fibrinogen;

    Sammanfattning : .... LÄS MER

  5. 4. Signaling mechanisms in Streptococcal M1 proteininduced inflammation and injury in the lung

    Författare :Songen Zhang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. Acute lung injury is recognized as a key component in the pathophysiology of streptococcal M1 proteininduced inflammation. LÄS MER

  7. 5. On the induction of inflammatory reactions by Streptococcus pyogenes

    Författare :Lisa Påhlman; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; virology; bacteriology; Microbiology; Streptococcal collagen-like surface protein; M protein; Inflammation; Streptococcus pyogenes;

    Sammanfattning : Streptococcus pyogenes is an important human pathogen that causes significant morbidity and mortality worldwide. In order to successfully infect the human host, S. pyogenes is equipped with tools that modulate the human immune defence. LÄS MER