Sökning: "M-like proteins"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden M-like proteins.

  1. 1. Interactions between Streptococcus pyogenes and the human immune system, with special reference to C4b-binding protein

    Författare :Anette Thern; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Phagocytosis; M-proteins; M-like proteins; Bovine C4b-binding protein; Streptococcus pyogenes; Human C4b-binding protein; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : The ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. LÄS MER

  3. 2. Immunoglobulin-binding bacterial surface proteins; biomedical tools and virulence factors

    Författare :Britt-Marie Kihlberg; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phagocytosis; M-like protein; M protein; Protein L; Protein G; Ig-binding; Streptococcus pyogenes; Fc Receptors; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; Cysteine proteinase; Streptolysin;

    Sammanfattning : Many bacteria express immunoglobulin(Ig)-binding proteins that interact with Ig in a non-immune manner. Several of these Ig-binding bacterial proteins have been well characterized and are widely used as reagents for analysis and purification of Ig's. LÄS MER

  4. 3. Evolutionary and functional studies of protein H: a surface molecule of Streptococcus pyogenes

    Författare :Inga-Maria Frick; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular transportation; adhesion; aggregation; FNIII domain; albumin-binding; M-like protein; convergent evolution; protein G; Streptococcus pyogenes; IgG-binding; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Several bacterial species express surface proteins with affinity for the Fc part of human IgG. This thesis describes evolutionary and functional studies of protein H, an IgGFc-binding surface protein of the human pathogen Streptococcus pyogenes. LÄS MER

  5. 4. Temperature-dependent structure and function of group A streptococcal M proteins

    Författare :Tommy Cedervall; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; plasma protein; fibrinogen; temperature; hydrophobicity; coiled-coil; Ig-binding; M protein; group A streptococcus; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Temperature-dependent structure and function of group A streptococcal M proteins.This thesis describes the temperature-dependent structure of the members in the group A streptococcal M protein family. M proteins are cell-surface proteins that are important for the bacterial virulence and bind to a diverse set of human plasma proteins. LÄS MER

  7. 5. Plasminogen and protein PAM: Interactions between streptococcal surface proteins and the human fibrinolytic system

    Författare :Annika Carlsson Wistedt; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; M protein; streptokinase; kringles; plasmin; Streptococcus pyogenes; plasminogen; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Pathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. LÄS MER