Sökning: "M proteins"
Visar resultat 11 - 15 av 366 avhandlingar innehållade orden M proteins.
11. Targeting Infectious Disease : Structural and functional studies of proteins from two RNA viruses and Mycobacterium tuberculosis
Sammanfattning : The recent emergence of a number of new viral diseases as well as the re-emergence of tuberculosis (TB), indicate an urgent need for new drugs against viral and bacterial infections.Coronavirus nsp1 has been shown to induce suppression of host gene expression and interfere with host immune response. LÄS MER
12. Regulation of midbrain dopaminergic neuron development by Wnts, sFRPs and bHLH proteins
Sammanfattning : Parkinson’s disease (PD) is a chronic neurodegenerative disorder. The main pathology is characterized by progressive degeneration of the dopaminergic (DA) neurons of the substantia nigra leading to loss of striatal dopamine innervation. The knowledge about the fundamental mechanisms behind the degenerative process has been limited. LÄS MER
13. Imaging of lipids and proteins in Alzheimer's disease using Time-of-Flight Secondary Ion Mass Spectrometry
Sammanfattning : Alzheimer’s disease (AD) is a neurodegenerative disease characterized by the formation of senile plaques. These plaques, which consist of aggregations of a peptide called amyloid-β, are deposited in-between the nerve cells in the brain, where they disrupt the signaling processes. LÄS MER
14. Membrane Protein Tailoring and Structural Studies of Leukotriene C4 Synthase
Sammanfattning : Despite a dramatic increase in the number of proteins that have been structurally characterized in recent years, there are still less than 200 unique structures of membrane proteins known today. This is only 1% of the total number of unique protein structures found in structural databases worldwide. LÄS MER
15. On the application and validation of multiplexed affinity assays
Sammanfattning : Proteins are essential macromolecules that carry out complex functions in human cells, tissues, and organs. They regulate a diverse set of biological processes and protect against pathogens. However, dysregulation or malformation of proteins can cause disease. LÄS MER