Sökning: "Lysine"
Visar resultat 1 - 5 av 149 avhandlingar innehållade ordet Lysine.
1. Therapy with 177Lu-octreotate - pharmacokinetics, dosimetry and kidney toxicity
Sammanfattning : 177Lu-octreotate is used for treatment of patients with somatostatin receptor expressing neuroendocrine tumors in some clinics using a standard schedule. Renal and bone marrow toxicity are the main limiting factors. LÄS MER
2. Cell-Penetrating Penetratin Peptides - Mechanistic Studies on Uptake Pathways and DNA Delivery Efficiency
Sammanfattning : Delivery of gene-targeted drugs is limited by the inherently poor capacity of nucleic acids to overcome the membrane barrier of the cell, and development of vectors that can promote uptake is therefore crucial. Cell penetrating peptides (CPPs) have emerged as promising vector candidates due to their ability to deliver a wide range of macromolecular cargos into cells. LÄS MER
3. Structure and distribution of alpha-1-microglobulin proteins
Sammanfattning : This thesis describes studies of the structure and tissue distribution of alpha-1-microglobulin (a1-m), a member of the lipocalin protein superfamily with immunosuppressive properies. It was shown that a1-m appears in human plasma in five major forms. LÄS MER
4. POLYPEPTIDES - STRUCTURES AND INTERACTIONS IN MONOLAYERS AND AQUEOUS SOLUTIONS
Sammanfattning : The aim of this thesis work is to understand and be able to control polypeptide conformation and interactions at interfaces and in solution by changing the solution conditions. For this purpose simple model polypeptides, so-called polyamino acids, have been investigated at the air-liquid interface, as well as in aqueous solutions. LÄS MER
5. Engineering synthetic pathways for adipic acid biosynthesis
Sammanfattning : Utilization of petroleum in consumer product manufacturing is causing irreversible environmental damage. Its impact on land, sea, and air calls for the development of more sustainable technologies based on the use of renewable materials such as lignocellulosic biomass and its conversion into platform chemicals. LÄS MER