Sökning: "Lung slices"

Hittade 5 avhandlingar innehållade orden Lung slices.

1. 1. Models of alveolar remodeling in chronic lung disease

   Författare :Oskar Rosmark; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix ECM ; Decellularization; Mass Spectrometry MS ; Biomechanics; Chronic obstructive pulmonary disease COPD ; Idiopathic pulmonary fibrosis IPF ; Alveolar epithelial cells; Fibroblasts; Lung slices;

   Sammanfattning : Lung function is highly dependent on the structure of the lung parenchyma. Remodeling of the alveolar compartment is a central part of the pathology of chronic lung disease such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). LÄS MER

3. 2. Nitric oxide and eicosanoids : significance and interactions during antigen-induced responses in peripheral lung tissue

   Författare :Anna-Karin Larsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Nitric oxide; leukotrienes; prostaglandins; histamine; ovalbumin; contractions; distal lung; rat; human; guinea pig; precision-cut lung slices; mast cell;

   Sammanfattning : Asthma means difficulty in breathing and is described as a chronic, inflammatory disorder that produces narrowing of the lower respiratory tract. The allergen-induced asthmatic bronchoconstriction is primarily caused by an IgE-mediated release of the mast cell mediators, histamine and eicosanoids (leukotrienes and prostanoids). LÄS MER

4. 3. Development of methods for evaluation and optimization of chest tomosynthesis

   Författare :Angelica Svalkvist; Göteborgs universitet; []
   Nyckelord :Chest tomosynthesis; Evaluation; Optimization; Simulation; Image Quality; Dosimetry; Dose reduction; Nodule simulation; Validation;

   Sammanfattning : Tomosynthesis is a low-dose technique that has attracted increasing interest from the medical imaging community during the past decade. Tomosynthesis refers to the technique of acquiring a number of projection radiographs using extremely low exposure over a limited angular range, and using these radiographs to reconstruct slices of the imaged object. LÄS MER

5. 4. Protein misfolding and amyloid formation : strategies for prevention

   Författare :Charlotte Nerelius; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Most proteins need to adopt a three-dimensional structure in order to function properly. Misfolding, or inability of proteins to fold, is associated with a number of diseases. In a subset of these disorders, the misfolded protein or peptide selfassembles into stable, β-sheet rich structures known as amyloid fibrils. LÄS MER

7. 5. The dependency of image quality on acquisition protocol and image processing in chest tomosynthesis

   Författare :Masoud Jadidi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The digital tomosynthesis (DTS) technique is a next generation of the old tomography technique, the use of which has been extended during the past decade. The interest in this technique has increased more and more in Radiology due to its ability to provide threedimensional images by acquiring a number of projection radiographs at lower radiation dose and potentially lower cost than CT in certain clinical situations. LÄS MER