Sökning: "Lund Pediatrik"

Visar resultat 11 - 15 av 95 avhandlingar innehållade orden Lund Pediatrik.

1. 11. Computer-assisted surgery in children

   Författare :Magnus Anderberg; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; minimally invasive; learning curve; laparoscopy; fundoplication; da Vinci® Surgical System; costs; Children; computer-assisted; paediatric surgery; robot; robotic surgery;

   Sammanfattning : Although positive in terms of patient trauma and recovery time, minimally invasive surgery has several technical drawbacks compared with open surgery. The new da Vinci® Surgical System from Intuitive Surgical® offers technical innovations aiming at overcoming these drawbacks and at improving the surgeon’s operating skills, such as the improved 3-D vision, tremor reduction and flexible instruments with a more natural and intuitive range of motion. LÄS MER

3. 12. Complement-mediated kidney diseases: Genotype, phenotype and inhibition studies

   Författare :S.S. Aradottir; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; The complement system; factor B; factor D; danicopan; Atypical hemolytic uremic syndrome; C3 glomerulopathy; Membranoproliferative glomerulonephritis; genes; monozygotic twins;

   Sammanfattning : Complement-mediated kidney diseases are ultrarare conditions characterized by excess complement activation related in most cases to complement gene variants or circulating autoantibodies. These conditions are chronic and can lead to kidney failure. LÄS MER

4. 13. Studies of the pathogenesis of Shiga toxin-producing Escherichia coli-induced hemolytic uremic syndrome

   Författare :Ida Arvidsson; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EHEC; hemolytic uremic syndrome; Shiga toxin; complement; hemolysis; microvesicles; cathelicidin;

   Sammanfattning : Hemolytic uremic syndrome (HUS) is characterized by non-immune hemolytic anemia, thrombocytopenia and acute kidney failure. The most common form of HUS is associated with gastrointestinal Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) infection. EHEC are non-invasive strains with Shiga toxin as the unique virulence factor. LÄS MER

5. 14. Studies of EHEC and the complement system in renal diseases

   Författare :Zivile Békassy; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EHEC; hemolytic uremic syndrome; thrombotic microangiopathy; atypical hemolytic uremic syndrome; alternative pathway of complement; dense deposit disease; eculizumab;

   Sammanfattning : This thesis addressed the diagnosis, pathogenesis and clinical course of specific renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD). HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). LÄS MER

7. 15. Primary immunodeficiency in southern Sweden. Strategies for diagnosis and clinical management

   Författare :Nicholas Brodszki; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune system; Lymphocytes; T-cell; B-cell; Antibodies; Complement system; Epidemiological study; Primary immunodeficiency; Severe combined immunodeficiency; Hematopoietic stem cell transplantation;

   Sammanfattning : The overall aim of this PhD project was to gain insight into the incidence of primary immunodeficiency (PID) in southern Sweden and to optimize diagnostic and treatment measures for these patients. We estimated the occurrence rate of PID in the pediatric population of southern Sweden during a period of 4 years and described the demographic, clinical and immunological characteristics of the identified cases. LÄS MER