Sökning: "LpL"
Visar resultat 6 - 10 av 41 avhandlingar innehållade ordet LpL.
6. Placental LPL and glucose metabolism in complicated pregnancies
Sammanfattning : BACKGROUND: Pregnancies complicated by intrauterine growth restriction (IUGR) or diabetes are associated with alterations in both lipid and glucose metabolism, which may lead to long lasting metabolic disturbances in the fetus and susceptibility for developing metabolic syndrome in postnatal life. Glucose is the major energy source for both the fetus and placenta. LÄS MER
7. Localization of lipoprotein lipase in mouse pancreas, kidney and placenta : impact of metabolic disturbances on cellular distribution and activity regulation
Sammanfattning : Lipoprotein lipase (LPL) is the key enzyme for metabolism of triglycerides in plasma lipoproteins. In recent years many new facts about the enzyme and its regulation have been uncovered. The endothelial membrane protein GPIHBP1 translocates LPL through endothelial cells and holds the enzyme in place at the luminal side of the capillary endothelium. LÄS MER
8. Lipoprotein lipase : mechanism for adaptation of activity to the nutritional state
Sammanfattning : Lipoprotein lipase (LPL) is an enzyme to hydrolyze triglycerides in lipoproteins and thereby make the fatty acids available for cellular metabolic reactions. Short-term fasting down-regulates LPL activity in adipose tissue. This regulation is through post-translational mechanism. LÄS MER
9. Aspects on lipoprotein lipase and atherosclerosis
Sammanfattning : Lipoprotein lipase (LPL) hydrolyses blood lipids at the vascular endothelium. This action makes fatty acids available for tissue metabolic requirements. LPL is anchored to the endothelium by electrostatic forces and may act as a bridge connecting lipoproteins to cell surfaces. LÄS MER
10. Lipoprotein lipase-unstable on purpose?
Sammanfattning : Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. It is a non-covalent, homodimeric and N-glycosylated protein, which is regulated in a tissue-specific manner and is dependent on an activator protein, apolipoprotein CII. Dissociation of active LPL dimers to monomers leads to loss of activity. LÄS MER