Sökning: "Low molecular weight heparin"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden Low molecular weight heparin.

  1. 1. Heparan sulfate dependent cell signaling and associated pathophysiology : Implications in tumorigenesis and embryogenesis

    Författare :Tahira Batool; Jin-Ping Li; Aristidis Moustakas; Liliana Schaefer; Ingvar Ferby; Michael Welsh; Anders Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Glucuronyl-C5 epimerase; Heparan Sulfate; Heparin; Lung Cancer; Cancer cell Singling; TGF-Beta; BMP; VEGF; Notch Signaling; Tumor growth; Metastasis; embryonic development; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Heparan sulfate proteoglycans (HSPGs) consist of a protein core to which several linear, negatively charged heparan sulfate (HS) chains are covalently attached. HSPGs are expressed on the cell surface and in the extra-cellular matrix (ECM) where they have diverse biological functions, for example co-receptor functions. LÄS MER

  3. 2. Lipoprotein lipase in hemodialysis patients and healthy controls : effects of heparin

    Författare :Birgit Näsström; Per-Ola Attman; Umeå universitet; []
    Nyckelord :dalteparin; dialysis; lipoprotein metabolism; LMWH; LPL; triglycerides; UFH; uremia; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

    Sammanfattning : Mortality from cardiovascular disease in patients on chronic hemodialysis (HD) is 10 to 20 times greater than in the general population. One major risk factor is renal dyslipidemia, characterised by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. LÄS MER

  4. 3. Clinical aspects on treatment of deep venous thrombosis with a low molecular weight heparin

    Författare :Margareta Holmström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Dalteparin is a low molecular weight heparin (LMWH) with a mean mw of 4-6000 D. Compared to unfractionated heparin (UFH), a higher bioavailability, a longer half-life and a more predictable dose-response is achieved after subcutaneous injections. LÄS MER

  5. 4. Antithrombotic Effects of Activated Protein C and Heparins in Deep Arterial Injury

    Författare :Karl Malm; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; mutagenesis; protein S; protein C; heparin; bleeding; arterial thrombosis; animal model;

    Sammanfattning : The investigations presented in this thesis have evaluated different strategies to prevent thrombosis in an experimental model of deep arterial injury in rats. Unfractionated heparin (UFH) is often used to prevent thrombosis in microvascular surgery and in other vascular interventions, but a major drawback of UFH is increased bleeding. LÄS MER

  7. 5. Multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease

    Författare :Tomas Jernberg; Uppsala universitet; []
    Nyckelord :Medical sciences; ST-monitoring; electrocardiography; vectorcardiography; myocardial infarction; unstable angina; prognosis; low-molecular-weight heparin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : This study evaluated the use of multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease (UCAD).At continuous 12-lead ECG (c12ECG), the definition of an ischemic episode as a transient ST-deviation ¡Ý0 for at least 1 minute resulted in a good observer agreement (kappa=0. LÄS MER