Sökning: "Ljungan virus"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Ljungan virus.
1. Ljungan Virus Replication in Cell Culture
Sammanfattning : Ljungan virus (LV) is a recently identified picornavirus of the genus Parechovirus. LV has been isolated from voles trapped in Sweden and also in the United States. LV infected small rodents may suffer from diabetes type 1 and type 2 like symptoms, myocarditis and encephalitis. LÄS MER
2. Apolipoprotein CIII and Ljungan virus in diabetes
Sammanfattning : It has been shown that there are patients with type 1 diabetes (T1D), whose sera induce an increased activity of voltage-gated Ca2+-channels in pancreatic beta-cells, resulting in increased cytoplasmic free Ca2+ concentration ([Ca2+]i) and apoptosis. Purification of the protein in the active fraction of T1D sera revealed that the observed effects were mediated by apolipoprotein CIII (apoCIII), and this protein was shown to be increased in serum from T1D patients. LÄS MER
3. Genomic Organization and Capsid Architecture of Ljungan Virus : a Novel Member of the Picornaviridae
Sammanfattning : Ljungan virus är ett virus som isolerades i Sverige i mitten på nittiotalet. Under perioden 1989-1992 avled flera svenska elitorienterare plötsligt i hjärtmuskelinflammation. Man misstänkte att orienterarna kunde ha utsatts för en vektorburen infektion eftersom de exponeras för djur som finns i skog och mark under träning och tävling. LÄS MER
4. Ljungan virus : a novel pathogen : effects on the pregnant female and her offspring
Sammanfattning : Ljungan virus (LV) was isolated in the mid 1990s from a native rodent, the bank vole (Myodes glareolus), trapped in the Ljungan valley of central Sweden. It is a member of the parecho virus genus in the picorna virus family. LÄS MER
5. Markers of Infection in Childhood Autoimmune Diabetes and Related Disorders
Sammanfattning : The main aim of this thesis was to contribute to the knowledge about mechanisms involved in the development of type 1 diabetes (T1D) and other autoimmune diseases in children. Immune markers in relation to genetic propensity in children with autoimmune disease, mainly T1D and a small group of juvenile idiopathic arthritis (JIA) and thyroiditis (THYR), as well as healthy controls have been studied. LÄS MER